BPC-157
for dogs & cats
MUSCLE, JOINT, Heart, brain & GUT SUPPORT
OVERVIEW
BPC-157, a peptide composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice, known for its potential to support repair, recovery, and various health benefits. It has been studied for its role in tendon repair, gastric ulcer healing, inflammation reduction, and neuroprotection.
BPC-157 has unique oral bioavailability. Unlike other peptides, it is highly effective when taken orally rather than via injection or nasal spray.
There are two dosages available in capsules from Infiniwell: a 250 mcg dose, ideal for those needing maintenance; and a 500 mcg dose, a higher potency that can be leveraged as a loading dose or applied to cases where more support is needed. The standard formulation of 250 mcg is recommended for use in dogs & cats.
In addition to the standard BPC-157 formulation, there are two time-release formula options (rapid and delayed) that combine BPC-157 with Salcaprozate Sodium (SNAC) to enhance absorption and support the body's ability to utilize the desired dosage.
SNAC is listed as “generally recognized as safe” (GRAS) for human consumption by the FDA. Safety of SNAC in dogs and cats in unknown.
The rapid release formula is typically for upper GI applications and is more appropriate for acute needs.
The delayed release works as ongoing support and is intended to reach the lower intestines without succumbing to the harsh environment of the upper digestive system.
DOSAGE FOR DOGS & CATS
The current recommendation is to go by the dosage protocol for an average sized human, to calculate the amount per pound, and then apply the same mcg/lb dosage to your pet.
Typical suggested dose for a 150 lb person is 250-500 mcg of BPC-157 orally each day (1.67- 3.33 mcg per lb body weight). This can be calculated for use in pets as follows:
|
Body Weight |
Acute/Loading Phase 1-3 weeks (2x/day) |
Low Daily Dose (1-2x/day) |
High Daily Dose (1-2x/day) |
|
5 lbs |
17 mcg |
8 mcg |
17 mcg |
|
10 lbs |
33 mcg |
17 mcg |
33 mcg |
|
25 lbs |
83 mcg |
42 mcg |
83 mcg |
|
35 lbs |
117 mcg |
58 mcg |
117 mcg |
|
50 lbs |
167 mcg |
84 mcg |
167 mcg |
|
65 lbs |
216 mcg |
109 mcg |
216 mcg |
|
75 lbs |
250 mcg |
125 mcg |
250 mcg |
|
90 lbs |
300 mcg |
150 mcg |
300 mcg |
|
100 lbs |
333 mcg |
167 mcg |
333 mcg |
For a more precise dose, you can multiply your pet’s body weight x 1.67 (low dose) or 3.33 (higher dose) to get their dose. Ideally, give this amount in divided doses, 2x/day.
Current research in dogs and rats showed that BPC-157 is nontoxic at even high doses.
Oral Capsules: Capsules are designed for easy digestion and offer a convenient option. Open capsules and mix the peptide powder with a meal or snack that provides some fat and protein.
BPC-157 dosing can vary based on the condition being treated. Here are some general dosing schedule guidelines for common conditions:
Acute Joint Injuries
Administered twice daily. The duration of treatment can vary, but it is often used until the injury shows significant improvement. Typically give the loading/acute dose for the first few days and then a low or high dose for a few weeks. Extended use is generally not required.
Brain Injuries
The frequency and duration is tailored to the patient’s response and the severity of the injury. Typically, give the loading/acute dose for a few weeks, then the lower or higher dose for up to 4 months.
Chronic GI Issues
Treatment duration can be longer, often extending over several weeks to months, depending on the patient’s condition and response to the peptide.
Duration of Use
The duration of BPC-157 use can vary widely. For acute conditions, it might be used for a few weeks, while for chronic conditions, it could be used for several months. It’s important to monitor the patient’s response and adjust the dosage and duration accordingly.
It’s always best to consult with a healthcare professional who can provide personalized recommendations based on the specific medical condition and individual needs.
KNOWN BENEFITS
- Joint (ligament & tendon), soft tissue repair & recovery
- repairs digestive system & supports functioning immune system
- neurological & CNS recovery (TBI, stroke, neurological disorders)
- endothelial nitric oxide production
RESEARCH has shown
- Improve healing of many types of wounds
- protect intestinal organs and prevents stomach ulcers
- combats leaky gut, IBS, gastrointestinal cramps and Crohn’s disease
- accelerate healing of skin burns
- works as an anti-inflammatory
- maintains integrity of mucosal lining GI tract
- repair tissues of gut, tendons, ligaments, brain, bone, etc.
- improves digestive function
NUTRITION
In response to tendon and ligament injury, BPC-157 supports healing by increasing type 1 collagen in these tissues. BPC-157 is cytoprotective and thus helps maintain the mucosal lining of the GI tract. As an anti-inflammatory, it supports the protection and healing of inflamed intestinal tissues. It also may play a role in tissue damage repair by increasing blood flow to damaged tissues. BPC-157 is stable in human gastric juice and has no reported toxicity.
BPC-157 For Pets
BPC-157, short for Body Protection Compound 157, is a naturally occurring peptide chain composed of 15 amino acids. It's found in our digestive systems – including those of our canine companions.
How does BPC-157 work?
- Promotes Growth Factors:BPC-157 may promote the production of growth factors, which are molecules that act as signals to cells, stimulating repair and renewal. It might especially influence a vascular endothelial growth factor (VEGF), which plays a role in creating new blood vessels.
- Reduces Inflammation: Inflammation is a normal part of the healing process, but excessive inflammation can hinder recovery and contribute to chronic conditions. BPC-157 has been shown to possess anti-inflammatory properties potentially helping manage discomfort.
- Supports Collagen Synthesis:Collagen is a major structural protein in tendons, ligaments, and skin. BPC-157 may help encourage collagen production, potentially aiding in tissue strength and health.
- Promotes Blood Flow:Healthy blood circulation is crucial for delivering oxygen and nutrients to injured or damaged areas. BPC-157's potential influence on blood vessel formation suggests a positive impact on circulation as well.
Potential Benefits of BPC-157 for Pets
- Injury Recovery: accelerates the healing process for various injuries due to its multi-faceted beneficial effects.
- Muscle, Tendon, and Ligament Support:just like humans, pets can experience strain or damage to connective tissues such as the CCL/ACL. BPC-157's collagen-boosting and inflammation-managing effects have shown it to be of great benefit to individuals considering surgical treatment. In many cases, the results are significant enough that the individual is able to forgo surgery.
- Gastrointestinal Health: originally found in human gastric juice, it's not surprising that research has focused on the impact BPC-157 has on repairing and regulating the digestive system. It could be helpful for pet’s with inflammatory conditions of the gut, such as inflammatory bowel disease (IBD).
- Age-Related Decline:aging can make mammals less energetic, and all animals may experience age-related mobility issues. By supporting connective tissue health and overall well-being, BPC-157 could help enhance quality of life in seniors.
Research into BPC-157 is ongoing, and more studies focusing specifically on pets are needed to fully understand the range of benefits it may have to offer.
ADMINISTRATION
BPC-157 given orally (capsules) has received attention as a potential treatment for a number of medical conditions, most notably Inflammatory bowel syndrome and healing of stomach ulcers.
Given by injection, research has shown benefits for musculoskeletal injuries, such as injuries of tendons and ligaments, muscle injuries, nerve injuries, bone fractures, tendinopathies like tennis elbow or Achilles tendinopathy.
Because BPC enhances the nitric oxide pathway, which is a vasodilator, more oxygen is delivered to the muscles, and oxygen exchange in the lungs is enhanced, BPC might improve endurance.
It also has been used to decrease pain in damaged tissues, making it a possible alternative to opioid drugs.
Oral Capsules: Capsules are designed for easy digestion and offer a convenient option. Open capsules and mix the peptide powder with a meal or snack that provides some fat and protein.
Do Capsules Work?
BPC-157 capsules are a common way to provide the peptide for pets. However, other methods (such as injection or nasal sprays) may be considered more effective due to direct delivery. However, as of this time, injections of BPC-157 are no longer permitted by the FDA; this is a recent change.
Fortunately, research suggests that BPC-157 can support healing, reduce inflammation, and promote collagen synthesis, whether taken orally or via injection. Just note that the bioavailability and effectiveness of oral capsules compared to injections can vary, and further studies are needed to fully understand this.
Is BPC-157 safe?
Current research suggests that BPC-157 considered safe for humans and other animals including dogs. Of course, as with any supplement or medication, it's always crucial to consult with your veterinarian before giving BPC-157. This is especially important if your pet has any underlying health conditions or is taking other medications.
Manufactured by a reputable company: Research the manufacturer and request information about the laboratory that they use to make their peptides. When researching the legitimacy and quality of a peptide laboratory, here are some key factors to consider:
- Third-Party Testing
Ensure the laboratory conducts third-party testing for purity, potency, and contaminants. Reputable labs will provide Certificates of Analysis (CoAs) from independent testing facilities.
- Transparency
Look for transparency in their processes. Legitimate labs will openly share their testing methods, results, and any quality control measures they have in place.
- Reputation and Reviews
Check for reviews and testimonials from other customers. Reliable sources often have positive feedback and a good reputation within the community.
- Regulatory Compliance
Verify that the lab complies with relevant regulations and standards. This includes adherence to Good Manufacturing Practices (GMP) and other industry-specific guidelines.
- Detailed Product Information
Quality labs provide detailed information about their products, including the source of raw materials, manufacturing processes, and storage conditions.
- Customer Support
Good customer support is a sign of a reputable company. They should be responsive and willing to answer any questions you have about their products and processes.
- Longevity and Experience
Consider how long the lab has been in operation and their experience in the field. Established labs with a history of quality and reliability are generally more trustworthy.
By keeping these factors in mind, you can better assess the legitimacy and quality of a peptide laboratory.
Lab Tested: Opt for products that have undergone third-party lab testing. This verifies purity, potency, and ensures the absence of harmful contaminants.
Transparent formulation: The ingredient list should be clear and easy to understand. Avoid products with artificial fillers or unnecessary additives.
Can Pets Take BPC-157?
Yes. Current research indicates that it is safe for use in pets, with potential benefits including enhanced recovery from injuries, support for muscle, tendon, and ligament health, and improved gastrointestinal health. It is recommended to consult with a knowledgeable veterinarian before administering BPC-157 to ensure it is appropriate for your pet’s specific health needs and condition.
BPC-157 presents an intriguing possibility for supporting our animals’ overall health and well-being. The potential for peptides such as BPC-157 for bolstering natural healing processes, addressing inflammation, and aiding joint health warrants continued investigation. While more pet-specific research is needed, what we know so far paints an optimistic picture.
Selected Sources
Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds: https://pubmed.ncbi.nlm.nih.gov/32334036/
Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794587/
BPC-157's effect on healing: BPC-157's effect on healing - ScienceDirect
Peptides In Veterinary Medicine: Peptides In Veterinary Peptides Medicine (bachem.com)
Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds: https://doi.org/10.1016/j.yrtph.2020.104665
Highlights
- BPC157 did not show any test-related effects in the single-dose toxicity study.
- BPC157 was well tolerated in repeated-dose toxicity evaluations.
- BPC157 caused mild local irritation and showed good tolerance.
- BPC157 showed no genetic or embryo-fetal toxicity.
Abstract BPC157 displays protective activity in various organs and tissues. This report presents preclinical toxicity studies with BPC157 in mice, rats, rabbits and dogs. The single-dose toxicity study did not show any test-related effects that could be attributed to the test article. In repeated-dose toxicity evaluations, BPC157 was well tolerated in dogs, with no abnormal changes between the BPC157-treated groups and the solvent control group, with the exception of a decrease in creatinine level at a dose of 2 mg/kg but not at lower doses. The animals recovered spontaneously after 2 weeks of withdrawal. This may be due to the pharmacological activity of BPC157. A local tolerance test showed that the irritation caused by BPC157 was mild. BPC157 also showed no genetic or embryo-fetal toxicity. In summary, BPC157 was well tolerated and did not cause any serious toxicity in mice, rats, rabbits and dogs. These preclinical safety data contribute to the initiation of an ongoing clinical study. Based on the stability and protective effect of BPC157, which has been widely reported, BPC157 may have a better application prospect than the widely used cytokine drugs in wound therapy.
THE BELOW EXCERPT IS TAKEN FROM THE “COCHRANE HANDBOOK”
Understanding BPC-157 involves looking into its mechanism of action, its role in the healing process, and its application in peptide therapy. BPC-157, a synthetic peptide derived from a protective protein found in the human stomach, exerts its healing effects by interacting with several biological pathways that promote tissue repair and regeneration. When administered, BPC-157 enhances:
- Blood flow to damaged tissues
- Accelerates the formation of new blood vessels
- Stimulates the production of growth factors, such as fibroblast growth factor and vascular endothelial growth factor, crucial for tissue rebuilding
This peptide has demonstrated anti-inflammatory properties, aiding in reducing inflammation and pain, thus creating an optimal environment for the body’s natural healing mechanisms to thrive.
BPC-157 offers a myriad of benefits, ranging from accelerated healing and tissue repair to potential growth hormone stimulation, but it also carries certain risks and side effects that need to be considered. Studies have shown that BPC-157 can effectively reduce inflammation and improve the healing process in various types of injuries, such as tendon, muscle, and ligament damage. Its regenerative properties make it a promising option for athletes looking to speed up recovery times and enhance performance. Moreover, BPC-157 has demonstrated neuroprotective effects and the ability to promote the repair of gastrointestinal ulcers, which has implications for those suffering from digestive disorders or seeking gut health improvement. It is important to note that while BPC-157 shows great potential, there is still limited long-term data available regarding its safety profile and possible interactions with other medications, highlighting the need for further research and caution when using this peptide.
Positive Effects
The positive effects of BPC-157 encompass its remarkable healing properties, therapeutic potential, and the convenience of oral administration through BPC-157 capsules.
Regarding aiding the body’s healing and recovery processes, BPC-157 stands out for its ability to support tissue repair. This peptide has shown promising results in promoting the mending of damaged tissues, including muscles, ligaments, and even the intestinal tract.
The therapeutic potential of BPC-157 extends beyond mere wound healing, with research suggesting its benefits for various medical conditions such as inflammatory bowel disease, tendonitis, and even nerve damage.
Potential Side Effects
BPC-157 potential side effects may include interactions with gastric juices in the intestinal area, leading to specific concerns that should be monitored. When BPC-157 comes in contact with gastric juices in the intestinal area, it may lead to digestive discomfort, such as bloating or mild stomach upset. These side effects are typically mild and transient, resolving on their own as the body adjusts to the peptide. If these symptoms persist or worsen over time, it is crucial to discontinue use and consult a healthcare professional for further evaluation. Regular monitoring of any unusual reactions is essential to ensure the safe use of BPC-157 and to address any potential risks promptly.
Administration Methods
BPC-157 can be administered through various methods, including oral administration using tablets, nasal sprays or injections, each with its unique benefits and considerations. Regarding oral administration through tablets, one of the key advantages is the convenience it offers. Tablets can be easily taken anywhere, without the need for needles or specialized equipment, making it a more user-friendly option. Additionally, tablets typically have a longer shelf life than liquid forms, providing greater stability. On the other hand, injections are known for their fast absorption rate, delivering BPC-157 directly into the bloodstream for immediate effect. This method may be preferred for individuals who require rapid results or have digestive issues that could impact tablet absorption.
Comparison: Tablets vs. Injections
The comparison between administering BPC-157 through tablets and injections involves considerations such as:
- Dosage accuracy
- Absorption rates
- Availability of research peptides
Regarding dosage accuracy, injections offer a more precise delivery method as the dosage can be controlled with higher granularity compared to tablets. With tablets, ensuring exact dosage can be challenging due to factors like individual variation in absorption rates. Bioavailability plays a crucial role in how effectively the peptide is utilized by the body.
Which is more effective? Injections typically provide higher bioavailability as the peptide bypasses the digestive system, leading to quicker absorption into the bloodstream. Research-grade peptides are often more readily available for injection methods, allowing for comprehensive studies on their efficacy and safety, which can have a significant impact on treatment outcomes and patient experience.
Dosage Guidelines (for 150-lb humans)
Establishing proper dosage guidelines for BPC-157 is crucial for maximizing its therapeutic benefits and ensuring safe usage, with recommendations tailored to individual needs and treatment objectives. Regarding determining the appropriate BPC-157 dosage, several factors must be considered, including the specific condition being treated, the severity of the symptoms, and the individual’s weight and overall health status.
Studies have shown that BPC-157 can be administered at varying doses, typically ranging from 200-500 mcg per day, depending on the desired effects. It is essential to divide the total daily dosage into smaller, equally spaced doses to maintain stable blood levels throughout the day.
Recommended Dosage and Frequency
The recommended BPC-157 dosage and frequency depend on factors such as:
- Therapeutic potential
- Desired outcomes
- Interaction with growth hormone levels in the body
When determining the appropriate dosage, it is crucial to consider the individual’s specific condition and the severity of symptoms.
Oral administration for mild to moderate conditions, a typical starting dose ranges from 250-500 micrograms per day, administered orally or subcutaneously. In cases of more severe injuries or chronic issues, dosages may be higher, with some protocols suggesting up to 1,000 micrograms per day. Frequency of administration can vary widely, but common recommendations include once or twice daily for general healing and tissue repair purposes. For performance enhancement or athletic recovery, some experts advocate for dosing multiple times per day for optimal results.
Injectable administration is preferable for treating injuries. The ideal injectable dosage range for humans taking BPC-157 is: 250mcg to 500mcg per day
Inject either once or twice a day. Use BPC-157 as long as needed to heal the injury. There is no need to cycle off of it.
Results and Timeline
Tracking the results of BPC-157 treatment and understanding the healing timeline can offer valuable insights into its effectiveness and impact on the body’s healing processes. Research and clinical trials have shown that patients undergoing BPC-157 treatment have experienced:
- Accelerated wound healing
- Reduced inflammation
- Improved muscle and tendon recovery
Many individuals observed decreased pain and increased mobility within a few weeks of starting the treatment. In a study conducted on athletes with sports-related injuries, the majority reported significant improvements in their condition after just a few weeks of using BPC-157. These positive outcomes were attributed to the peptide’s ability to enhance tissue repair and modulate various molecular pathways involved in the healing process.
Expected Results
Anticipating the expected results of BPC-157 treatment involves considering its effects on tissue repair, regenerative properties, as demonstrated in animal models and scientific studies. Animal model studies have revealed the profound impact of BPC-157 on accelerating the healing process of tendons, ligaments, muscles, and various other tissues. The peptide has shown promising results in enhancing the synthesis of collagen, a crucial protein for tissue strength and repair. Scientific data suggest that BPC-157 may aid in reducing inflammation and promoting angiogenesis, the formation of new blood vessels crucial for tissue regeneration.
Patients undergoing BPC-157 therapy often experience:
- Quicker recovery times
- Reduced pain levels
- Improved overall functionality of the treated area
The therapy’s regenerative properties play a vital role in enhancing tissue repair mechanisms and supporting long-term healing outcomes.
Disclaimer
The Cochrane Handbook (www.cochrane-handbook.org) is a comprehensive resource promoting evidence-based healthcare practices. While the information provided on this website is intended for educational and research purposes, it is important to understand the limitations and appropriate use of the content. • The Cochrane Handbook and its linked resources provides information about healthcare interventions, treatments and research procedures. This information includes any referenced scientific or clinical research. The Cochrane Handbook makes no claims about how the action or treatment presented can cure, treat or prevent any medical conditions or diseases. • The Cochrane Handbook upholds the highest research integrity, standards, and ethical conduct. All research referenced on this website complies with national and international regulations and guidelines for clinical trial information. The Cochrane Handbook is dedicated to the timely disclosure of the design and results of interventional clinical studies, ensuring transparency and accessibility. • Cochrane Handbook research findings should not be interpreted as conclusive or definitive. The Cochrane Handbook encourages critical evaluation and further investigation of the presented information. • Individuals seeking medical advice or treatment for any condition should avoid using the Cochrane Handbook as a substitute for professional medical consultation. It is advisable to consult with qualified healthcare providers for personalized medical advice and treatment. • Statements and opinions expressed on the Cochrane Handbook website or in its publications are those of the individual authors or contributors and may not necessarily reflect the views or positions of the Cochrane Handbook or its affiliated organizations.
©2024 Cochrane Handbook. All rights reserved.
KPV
- Anti-inflammatory
- Accelerates cutaneous wound healing
- Promotes gut health
KPV is a naturally occurring tri-peptide that consists of Lysine, Proline, and Valine. It is found at the end terminal of the alpha-melanocyte-stimulating hormone (alpha-MSH), which is produced by the pituitary gland. This pept1-mediated tripeptide KPV is able to exert its effect in the body through the PepT1 transporter, which is normally expressed in the small intestine
- Promotes a balanced immune response and supports healthy mast cell function.
- Substantially well-known for its anti-microbial and anti-inflammatory properties. It has pronounced effects on your gut as well as skin health.
- A potent anti-inflammatory substance which suppresses NFκB, a proinflammatory cytokine and therefore inhibits inflammation and the drastic effects that are followed by it.
- Exerts antimicrobial properties, protecting the body from opportunistic infections.
- Modulates collagen deposition to reduce scarring while speeding up the process of wound healing.
Anti-Inflammatory Effects
Due to its anti-inflammatory properties, most of its effects can be observed in patients with autoimmune diseases that are usually characterized by inflammation. Perhaps the anti-inflammatory effects are more prominently seen in the human gastrointestinal tract, as human trials involving KPV have shown that it can potentially treat inflammatory bowel diseases (IBD).
One such subtype of inflammatory bowel disease (IBD) is Ulcerative Colitis, a chronic, relapsing inflammatory disease of the colon in which inflammation impairs the colonic mucosal barrier and increases the chance of bacterial invasion into underlying tissues. KPV alleviates inflammation and promotes mucosal healing, thereby preventing further damage (6).
Treating Allergies
KPV has proven to be effective in targeting airway inflammation in lung diseases, thus making it a useful therapy for inflammatory pulmonary disease. This also theoretically makes KPV effective in treating allergic reactions as well (8).
Considering the cosmetic benefits of KPV, it can be used to treat cutaneous wounds with minimal scarring alongside other dermatologic conditions. Moreover, this tripeptide KPV is also known for its improved cutaneous wound healing characteristics. This may include allergic contact dermatitis and psoriatic syndromes that may be characterized by itching, inflammation, and redness of the skin.
THYMOGEN WITH IMMUNE PEPTIDE A2 (IPA2)
Thymogen with Immune Peptide A2 (IPA2) is a blend of immune-modulating dipeptides, Glu-Tryp (thymogen) and Lys-Glu (IPA2), surpassing thymosin alpha-1 in efficacy. Backed by clinical trials and metabolic testing, this combination demonstrates potent antimicrobial effects and enhances immunity, normalizing lymphocyte counts, boosting thymus activity, and reducing hTGFb. Both components aid in infection management and immune balance, with thymogen benefiting various conditions and IPA2 countering aging symptoms and cancer incidence.
Thymogen Alpha-1: A Comprehensive Analysis of the Synergistic Peptide Combination
Thymogen Alpha-1 represents an innovative approach to immune system support through its unique combination of bioregulator dipeptides. This product has gained attention in the field of peptide therapy for its potential to deliver superior immune modulation compared to traditional immune-supporting compounds.
COMPOSITION AND MECHANISM OF ACTION
Thymogen Alpha-1 contains a synergistic blend of two key bioregulator dipeptides: Thymogen (Glu-Tryp) and Immune Peptide A2 (Lys-Glu), each typically dosed at 250 mcg. This formulation is designed to mimic and potentially exceed the effectiveness of Thymosin Alpha-1, a 28-amino acid peptide originally isolated from the thymus gland that has been extensively studied for its immune-modulating properties.
The thymus gland plays a critical role in immune function, producing T cells and facilitating their maturation. As we age, thymus function naturally declines, leading to decreased T cell production and potentially compromised immune response. Thymogen Alpha-1 aims to support this aspect of immune function through its bioactive peptides.
HOW IT WORKS
The mechanism of action for these peptides involves several immune pathways:
- T-cell Regulation: The formulation stimulates T-cell differentiation and regulates peptide-MHC complexes, which are crucial for proper immune recognition and response.
- Lymphocyte Normalization: Clinical observations suggest the peptides help normalize lymphocyte counts and increase the functional activity of T cells.
- Cytokine Modulation: The peptides affect cytokine production, helping to regulate inflammatory processes and immune cell communication.
BENEFITS AND APPLICATIONS
Immune System Enhancement
Thymogen Alpha-1 is primarily marketed for its ability to support and modulate immune function. Research suggests that this peptide combination may:
- Support white blood cell activity and function
- Aid in normalizing lymphocyte counts
- Boost thymus activity, potentially counteracting age-related decline
- Provide antimicrobial effects through enhanced immune response
Inflammation Management
One of the notable properties of Thymogen Alpha-1 is its potential to regulate inflammatory processes. This may be particularly beneficial in:
- Supporting the body's natural anti-inflammatory response
- Helping balance immune reactivity through T regulatory cells (Tregs)
- Potentially addressing chronic inflammatory conditions
Clinical Applications
Based on the available research, Thymogen Alpha-1 may offer support for various health challenges:
- Immune Dysfunction: The peptide combination may help address various forms of immune dysfunction, with research suggesting potential benefits for autoimmune conditions like lupus and rheumatoid arthritis.
- Chronic Infections: There is evidence suggesting efficacy against hepatitis B and C, with some research indicating potential support for those with Lyme disease.
- Metabolic Support: Research has shown promise for addressing type 1 diabetes with secondary immunodeficiency, with one study reporting 94.4% clinical efficacy.
- Inflammatory Conditions: Clinical studies have demonstrated effectiveness in treating acute endometritis, an inflammatory condition of the female genital tract.
- Cancer Support: The peptide combination may provide adjunctive support for various cancers and potentially reduce cancer incidence through immune modulation.
FORMULATION AND DOSAGE
Thymogen Alpha-1 is typically available as an oral supplement. The standard dosage is 250mcg (of each peptide) taken twice daily.
Ingredients
The typical formulation includes:
- Thymogen (Glu-Tryp): 250mcg
- Immune Peptide A2 (Lys-Glu): 250mcg
Scientific Evidence and Development
Thymogen Alpha-1 was developed using metabolomics technology, which measures metabolites from various chemical reactions to optimize the peptide combination. According to product literature, this formulation has been shown to replace and potentially outperform the traditional peptide thymosin alpha-1 in clinical trials and published literature.
Notably, while thymosin alpha-1 (under the brand name Zadaxin) has been approved in over 35 countries for treating conditions like hepatitis B and C, the FDA no longer allows production of Thymosin Alpha-1 in the United States. Thymogen Alpha-1 is positioned as an alternative that may provide similar or superior benefits through its unique peptide combination.
CONCLUSION
Thymogen Alpha-1 represents an innovative approach to immune system support through its combination of Thymogen (Glu-Tryp) and Immune Peptide A2 (Lys-Glu). With potential benefits for immune modulation, inflammation management, and various clinical applications, this peptide formulation offers promising support for overall health and wellness. As with any supplement, individuals should consult healthcare providers before beginning use, particularly those with existing medical conditions or those taking other medications.
